The aim of this study was to evaluate the effectiveness of cognitive schema therapy on reducing anxiety and depression in women with breast cancer in Tehran. The research method was a quasi-experimental type of pretest-posttest with a control group. Available or selected voluntarily. Then, the experimental and control groups of 30 were randomly assigned. The twelve-session protocol of Yang schema therapy was performed on the experimental group. Both groups completed the Goldberg and Hiller (1979) General Health Questionnaire in the pre-test and post-test. The results of multivariate analysis of variance showed that Schema therapy was significant in reducing anxiety and depression (p <0.001). Based on this, it can be said that cognitive schema therapy can reduce anxiety and depression in women with breast cancer. For future research, this treatment can be considered as an effective factor in improving the condition of breast cancer patients and increasing their mental health.

Keywords: Schema Therapy, Depression, Anxiety, Breast Cancer.

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